Current status

In October 2024, the below number of individuals have been recruited in Swedegene. DNA and clinical data collection for these are completed.

ADR type Number
Angioedema 540
Anaphylaxis 148
Urticaria 201
Other allergic reactions 127
Cough related to ACE-inhibitors 148
Osteonecrosis and atypical fractures due to bisphosphonates 144
Phototoxic reactions (mainly due to topical NSAIDs) 51
Blood cell dyscrasia (agranulocytosis, thrombocytopenia and anemia) to non-cytostatic drugs  302
Metabolic reactions from neuroleptics and antidepressants (mainly weight gain) 72
Hyponatremia/SIADH due to antidepressants and antiepileptics 41
CNS toxicity and neuropsychiatric reactions from antiviral therapy and antibiotics 95
Stevens-Johnson syndrome/Toxic epidermal necrolysis 67
Tendon-rupture from flouroquinolones 33
Liver toxicity 469
Rhabdomyolysis related to statins/fibrates 52
Torsade de Pointes/QT-prolongation 24
Narcolepsy associated with Pandemrix 85
Hypersomnia associated with Pandemrix 14
Pancreatitis 101
Alopecia 27
Bleedings from new oral anticoagulants (NOACs) 160
Lack of efficacy of NOACs 33
Pneumonitis 44
Renal toxicity 103
Ankle oedema from calcium channel blockers 46
Gingival hyperplasia from calcium channel blockers 17
Adverse reactions to Covid-19 vaccines 881
Thyroiditis 18
Gastrointestinal reactions to medication for Parkinson’s disease 2
Controls 568
Total number of cases 4613

ACE = angiotensin converting enzyme; NSAID = non-steroidal anti-inflammatory drug; NOAC=non-vitamin K oral anticoagulant drug.

Note that the number of cases for a particular ADR may be greater than the total number of cases as some individuals have experienced multiple ADRs concomitantly.